BDBM17697 2-aminobenzoxazole, 22::4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}phenyl)amino]-1,3-benzoxazol-5-yl}oxy)-N-methylpyridine-2-carboxamide

SMILES CNC(=O)c1cc(Oc2ccc3oc(Nc4ccc(Cl)c(OC[C@@H]5CCCN5C)c4)nc3c2)ccn1

InChI Key InChIKey=KMNCFOUKJYOZIF-KRWDZBQOSA-N

Data  1 KI  10 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17697   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM17697(2-aminobenzoxazole, 22 | 4-({2-[(4-chloro-3-{[(2S)...)
Affinity DataIC50:  80nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed